Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/124727
Type: Conference paper
Title: Fluid-structure analysis of an atherosclerotic coronary artery
Author: Gholipour, A.
Ghayesh, M.
Zander, A.
Nicholls, S.
Psaltis, P.
Citation: Proceedings of the 21st Australasian Fluid Mechanics Conference (AFMC 2018), 2018 / pp.1-4
Publisher: Australian Fluid Mechanics Society
Issue Date: 2018
ISBN: 9780646597843
Conference Name: 21st Australasian Fluid Mechanics Conference (10 Dec 2018 - 13 Dec 2018 : Adelaide, Australia)
Statement of
Responsibility: 
A. Gholipour, M. H. Ghayesh, A. Zander, S. J. Nicholls and P. J. Psaltis
Abstract: A theoretical fluid-structure interaction (FSI) model for the stress field of atherosclerotic coronary arteries are obtained and the influence of various characteristics on the stress distribution in diseased coronary arteries is highlighted. A reliable model is developed (and hence accurate heart attack prediction), the following factors are incorporated: (1) non-Newtonian blood flow; (2) artery’s tapered shape; (3) the micro-calcification of the plaque; (4) blood pulsation. Incorporating these factors in the model makes it possible to accurately predict plaque ruptures. The system is modelled based on a 3D fluid-structure interaction analysis via the finite element method (FEM). Experimental data from previous studies are used to generate a realistic material model. The generated model is utilised as a predictive model for plaque rupture and to determine high risk situations in the coronary arteries. It is shown that incorporating the physiological flow rate in the model, the wall shear stress (WSS) (stresses impose to the plaque from blood) and von Mises stresses (stresses in the plaque) are predicted accurately. Also it is shown that microcalcification increases the von Mises stress substantially in the plaque, when the WSS remains the same. Considering tapered shape of the artery is also shown to be important for predicting correct values of both shear and von Mises stresses.
Rights: Commencing with 19AFMC, the Society holds copyright to papers which appear in the Proceedings. Prior to that, copyright resides with authors of the papers.
RMID: 1000008378
Published version: https://people.eng.unimelb.edu.au/imarusic/proceedings/21%20AFMC%20TOC.html
Appears in Collections:Mechanical Engineering conference papers

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