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Type: Journal article
Title: Influence of clinical characteristics on maternal DHA and other polyunsaturated fatty acid status in pregnancy: a systematic review
Author: Wilson, N.
Mantzioris, E.
Middleton, P.
Muhlhausler, B.
Citation: Prostaglandins Leukotrienes and Essential Fatty Acids, 2020; 154:102063
Publisher: Elsevier
Issue Date: 2020
ISSN: 0952-3278
Statement of
N.A. Wilson, E. Mantzioris, P.F. Middleton, B.S. Muhlhausler
Abstract: INTRODUCTION: Omega-3 DHA is important for the prevention of preterm birth, however there is limited knowledge of the determinants of omega-3 status during pregnancy. The primary objective of this systematic review was to synthesise data from existing studies assessing relationships between clinical factors and maternal DHA status. MATERIALS AND METHODS: The Medline, Embase, Amed, and CINAHL databases were searched for studies reporting measures of maternal omega-3 status and one or more clinical characteristics. RESULTS: Eighteen studies were included in the final analyses. Factors associated with a higher BMI (overweight, higher gestational weight gain, gestational diabetes), or lower parity were each associated with higher omega-3 status in the majority of studies, with mixed findings for other comparisons. DISCUSSION: Inconsistent findings between studies make it difficult to draw clear conclusions about the relationship between clinical factors and maternal omega-3 DHA status. However, maternal overweight and associated metabolic conditions may increase lipid metabolism.
Keywords: BMI; DHA; Maternal status; Omega-3; Omega-6; Polyunsaturated fatty acids
Rights: © 2020 Elsevier Ltd. All rights reserved.
RMID: 1000014829
DOI: 10.1016/j.plefa.2020.102063
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Appears in Collections:Medicine publications

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