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|Title:||Influence of clinical characteristics on maternal DHA and other polyunsaturated fatty acid status in pregnancy: a systematic review|
|Citation:||Prostaglandins Leukotrienes and Essential Fatty Acids, 2020; 154:102063|
|N.A. Wilson, E. Mantzioris, P.F. Middleton, B.S. Muhlhausler|
|Abstract:||INTRODUCTION: Omega-3 DHA is important for the prevention of preterm birth, however there is limited knowledge of the determinants of omega-3 status during pregnancy. The primary objective of this systematic review was to synthesise data from existing studies assessing relationships between clinical factors and maternal DHA status. MATERIALS AND METHODS: The Medline, Embase, Amed, and CINAHL databases were searched for studies reporting measures of maternal omega-3 status and one or more clinical characteristics. RESULTS: Eighteen studies were included in the final analyses. Factors associated with a higher BMI (overweight, higher gestational weight gain, gestational diabetes), or lower parity were each associated with higher omega-3 status in the majority of studies, with mixed findings for other comparisons. DISCUSSION: Inconsistent findings between studies make it difficult to draw clear conclusions about the relationship between clinical factors and maternal omega-3 DHA status. However, maternal overweight and associated metabolic conditions may increase lipid metabolism.|
|Keywords:||BMI; DHA; Maternal status; Omega-3; Omega-6; Polyunsaturated fatty acids|
|Rights:||© 2020 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Medicine publications|
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