Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/125615
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Type: Journal article
Title: Ginsenoside Rg3: Potential molecular targets and therapeutic indication in metastatic breast cancer
Author: Nakhjavani, M.
Hardingham, J.E.
Palethorpe, H.M.
Tomita, Y.
Smith, E.
Price, T.J.
Townsend, A.R.
Citation: Medicines, 2019; 6(1):17-1-17-20
Publisher: MDPI
Issue Date: 2019
ISSN: 2305-6320
2305-6320
Statement of
Responsibility: 
Maryam Nakhjavani, Jennifer E Hardingham, Helen M Palethorpe, Yoko Tomita, Eric Smith, Tim J Price and Amanda R Townsend
Abstract: Breast cancer is still one of the most prevalent cancers and a leading cause of cancer death worldwide. The key challenge with cancer treatment is the choice of the best therapeutic agents with the least possible toxicities on the patient. Recently, attention has been drawn to herbal compounds, in particular ginsenosides, extracted from the root of the Ginseng plant. In various studies, significant anti-cancer properties of ginsenosides have been reported in different cancers. The mode of action of ginsenoside Rg3 (Rg3) in in vitro and in vivo breast cancer models and its value as an anti-cancer treatment for breast cancer will be reviewed.
Keywords: Ginsenoside Rg3; breast cancer; AQP-1; epimer; angiogenesis
Description: Published: 23 January 2019
Rights: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
RMID: 0030107477
DOI: 10.3390/medicines6010017
Appears in Collections:Surgery publications

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