Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/128230
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: A bout of voluntary running enhances context conditioned fear, its extinction, and its reconsolidation
Author: Siette, J.
Reichelt, A.
Westbrook, R.
Citation: Learning and Memory, 2014; 21(2):73-81
Publisher: Cold Spring Harbor Laboratory Press
Issue Date: 2014
ISSN: 1072-0502
1549-5485
Statement of
Responsibility: 
Joyce Siette, Amy C. Reichelt and R. Frederick Westbrook
Abstract: Three experiments used rats to examine the effect of a single bout of voluntary activity (wheel running) on the acquisition, extinction, and reconsolidation of context conditioned fear. In Experiment 1, rats provided with access to a wheel for 3 h immediately before or after a shocked exposure to a context froze more when tested in that context than rats provided with access to the wheels 6 h after the shocked exposure or rats not provided with access to the wheels. In Experiment 2, rats provided with access to the wheels immediately before or after a nonshocked exposure to the conditioned context froze less when tested in that context than rats provided with access to the wheels 6 h after the nonshocked exposure or rats not provided with access to the wheels. In Experiment 3, rats provided with access to wheels immediately after an extended nonshocked exposure to the conditioned context again froze less, whereas rats provided with access to the wheels after a brief nonshocked exposure froze more on the subsequent test than sedentary controls. These results show that a single bout of running can enhance acquisition, extinction, and reconsolidation of context conditioned fear.
Keywords: Animals
Rats
Rats, Wistar
Electroshock
Freezing Reaction, Cataleptic
Motor Activity
Fear
Conditioning (Psychology)
Memory
Running
Time Factors
Male
Extinction, Psychological
Rights: © 2014 Siette et al.; Published by Cold Spring Harbor Laboratory Press. This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date. After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http:// creativecommons.org/licenses/by-nc/3.0/
DOI: 10.1101/lm.032557.113
Grant ID: http://purl.org/au-research/grants/arc/DP110105136
Appears in Collections:Aurora harvest 8
Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.