Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/128419
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Type: Journal article
Title: Novel trial strategies to enhance the relevance, efficiency, effectiveness and impact of nephrology research
Author: Dansie, K.
Viecelli, A.K.
Pascoe, E.M.
Johnson, D.W.
McDonald, S.
Clayton, P.
Hawley, C.
Citation: Kidney International, 2020; 98(3):572-578
Publisher: Elsevier
Issue Date: 2020
ISSN: 0085-2538
1523-1755
Statement of
Responsibility: 
Kathryn Dansie, Andrea K. Viecelli, Elaine M. Pascoe, David W. Johnson, Stephen McDonald, Philip Clayton and Carmel Hawley
Abstract: Randomised Controlled Trials (RCTs) are considered the gold-standard for evaluating the effectiveness of interventions. However, criticisms of traditional designs are that they can be inefficient, inflexible, expensive and conducted in a manner disconnected from real-life clinical practice. Novel strategies and approaches are being utilised to overcome these limitations including comprehensive consumer engagement, core outcome sets, novel trial designs, streamlined data collection, cost-effectiveness and return on investment evaluations, knowledge dissemination plans and impact evaluation. These strategies can be implemented at the design, conduct, implementation and dissemination stages of the trial process. This review aims to provide an overview of these strategies and approaches to improve the relevance, efficiency, effectiveness and impact of nephrology research.
Keywords: chronic kidney disease
Rights: © 2020, International Society of Nephrology. Published byElsevier Inc. All rights reserved.
RMID: 1000021981
DOI: 10.1016/j.kint.2020.04.050
Grant ID: http://purl.org/au-research/grants/nhmrc/1092957
Appears in Collections:Medicine publications

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