Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Book chapter
Title: The role of biotin in bacterial physiology and virulence: A novel antibiotic target for Mycobacterium tuberculosis
Author: Salaemae, W.
Booker, G.W.
Polyak, S.W.
Citation: Virulence Mechanisms of Bacterial Pathogens, 2016 / Kudva, I.T., Cornick, N.A., Plummer, P.J., Zhang, Q., Nicholson, T.L., Bannantine, J.P., Bellaire, B.H. (ed./s), Ch.28, pp.797-822
Publisher: ASM Press
Publisher Place: Washington, DC.
Issue Date: 2016
ISBN: 1555819273
Editor: Kudva, I.T.
Cornick, N.A.
Plummer, P.J.
Zhang, Q.
Nicholson, T.L.
Bannantine, J.P.
Bellaire, B.H.
Statement of
Wanisa Salaemae, Grant W. Booker, and Steven W. Polyak
Abstract: Tuberculosis (TB) is a global pandemic that ranks alongside HIV-AIDS and malaria as the leading cause of death by infectious disease, with the highest incidence rates observed in Southeast Asian, African, and Western Pacific countries ( 1 ). In 1993 the WHO declared TB to be a global health emergency and set the Millennium Development Goal of reducing the prevalence and mortality rates to 50% of those observed in 1990 by the 2015 deadline ( 2 ). Although the rates of new TB cases and mortality have declined over the past decade and are within reach of the 2015 target, the number of TB patients and the prevalence of drug-resistant strains are rising ( 3 ). Multidrug-resistant TB (MDR-TB) must be addressed now as a public health crisis to achieve the ambitious Millennium Development Goal target of complete elimination of TB as a public health concern by 2050 ( 4 ).
Rights: © 2016 American Society for Microbiology
DOI: 10.1128/9781555819286.ch28
Published version:
Appears in Collections:Aurora harvest 8
Molecular and Biomedical Science publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.