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Type: Journal article
Title: The incidence of stroke in Indigenous populations of countries with a Very High Human Development Index: a systematic review protocol
Author: Balabanski, A.H.
Dos Santos, A.
Woods, J.A.
Thrift, A.G.
Kleinig, T.J.
Suchy-Dicey, A.
Siri, S.R.
Boden-Albala, B.
Krishnamurthi, R.
Feigin, V.L.
Buchwald, D.
Ranta, A.
Mienna, C.S.
Zavaleta, C.
Churilov, L.
Burchill, L.
Zion, D.
Longstreth, W.T.
Tirschwell, D.L.
Anand, S.
et al.
Citation: Frontiers in Neurology, 2021; 12:661570-1-661570-12
Publisher: Frontiers Media SA
Issue Date: 2021
ISSN: 1664-2295
Statement of
Anna H. Balabanski, Angela Dos Santos, John A. Woods, Amanda G. Thrift, Timothy J. Kleinig, Astrid Suchy-Dicey, Susanna Ragnhild Siri, Bernadette Boden-Albala, Rita Krishnamurthi, Valery L. Feigin, Dedra Buchwald, Annemarei Ranta, Christina S. Mienna, Carol Zavaleta, Leonid Churilov, Luke Burchill, Deborah Zion, W.T. Longstreth Jr., David L. Tirschwell, Sonia Anand, Mark W. Parsons, Alex Brown, Donald K. Warne, Matire Harwood, and Judith M. Katzenellenbogen
Abstract: Background and Aims: Despite known Indigenous health and socioeconomic disadvantage in countries with a Very High Human Development Index, data on the incidence of stroke in these populations are sparse. With oversight from an Indigenous Advisory Board, we will undertake a systematic review of the incidence of stroke in Indigenous populations of developed countries or regions, with comparisons between Indigenous and non-Indigenous populations of the same region, though not between different Indigenous populations. Methods: Using PubMed, OVID-EMBASE, and Global Health databases, we will examine population-based incidence studies of stroke in Indigenous adult populations of developed countries published 1990-current, without language restriction. Non-peer-reviewed sources, studies including <10 Indigenous People, or with insufficient data to determine incidence, will be excluded. Two reviewers will independently validate the search strategies, screen titles and abstracts, and record reasons for rejection. Relevant articles will undergo full-text screening, with standard data extracted for all studies included. Quality assessment will include Sudlow and Warlow's criteria for population-based stroke incidence studies, the Newcastle-Ottawa Scale for risk of bias, and the CONSIDER checklist for Indigenous research. Results: Primary outcomes include crude, age-specific and/or age-standardized incidence of stroke. Secondary outcomes include overall stroke rates, incidence rate ratio and case-fatality. Results will be synthesized in figures and tables, describing data sources, populations, methodology, and findings. Within-population meta-analysis will be performed if, and where, methodologically sound and comparable studies allow this. Conclusion: We will undertake the first systematic review assessing disparities in stroke incidence in Indigenous populations of developed countries. Data outputs will be disseminated to relevant Indigenous stakeholders to inform public health and policy research.
Keywords: Epidemiology; incidence; population; stroke; health; Aboriginal; Indigenous
Rights: © 2021 Balabanski, Dos Santos, Woods, Thrift, Kleinig, Suchy-Dicey, Siri, Boden-Albala, Krishnamurthi, Feigin, Buchwald, Ranta, Mienna, Zavaleta, Churilov, Burchill, Zion, Longstreth, Tirschwell, Anand, Parsons, Brown, Warne, Harwood and Katzenellenbogen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
DOI: 10.3389/fneur.2021.661570
Grant ID:
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