Application and Effectiveness of Online Interventions for Depression in Adults with Multiple Sclerosis

Abstract

Depression is common in the clinical presentation of multiple sclerosis (MS) and can lead to a range of adverse health outcomes. Online interventions provide a cost-effective, accessible treatment option for those who often have difficulty accessing face-to-face psychotherapy due to MS-related complications. There is preliminary evidence for the efficacy of online service delivery. However, this literature is characterised by small studies with passive control groups; methodological features which may overestimate intervention effects. This review examines the efficacy of online interventions targeted to the MS cohort, highlighting a need for high-quality randomised trials to establish a stronger evidence base.