Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/131649
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Type: Journal article
Title: Bioactive plasma coatings on orthodontic brackets: In Vitro metal ion release and cytotoxicity
Author: Kumarasinghe, L.
Ninan, N.
Dabare, P.
Cavallaro, A.
Dogramaci, E.
Rossi-Fedele, G.
Dreyer, C.
Vasilev, K.
Zilm, P.
Citation: Coatings, 2021; 11(11):857-1-857-11
Publisher: MDPI
Issue Date: 2021
ISSN: 2079-6412
2079-6412
Statement of
Responsibility: 
Lasni Samalka Kumarasinghe, Neethu Ninan, Panthihage Ruvini Lakshika Dabare, Alex Cavallaro, Esma J. Dogramacı, Giampiero Rossi-Fedele ... et al.
Abstract: The metal ion release characteristics and biocompatibility of meta-based materials are key factors that influence their use in orthodontics. Although stainless steel-based alloys have gained much interest and use due to their mechanical properties and cost, they are prone to localised attack after prolonged exposure to the hostile oral environment. Metal ions may induce cellular toxicity at high dosages. To circumvent these issues, orthodontic brackets were coated with a functional nanothin layer of plasma polymer and further immobilised with enantiomers of tryptophan. Analysis of the physicochemical properties confirmed the presence of functional coatings on the surface of the brackets. The quantification of metal ion release using mass spectrometry proved that plasma functionalisation could minimise metal ion release from orthodontic brackets. Furthermore, the biocompatibility of the brackets has been improved after functionalisation. These findings demonstrate that plasma polymer facilitated surface functionalisation of orthodontic brackets is a promising approach to reducing metal toxicity without impacting their bulk properties.
Keywords: orthodontic brackets; plasma polymerisation; amino acid;metal ion release; biocompatibility
Rights: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI: 10.3390/coatings11070857
Grant ID: http://purl.org/au-research/grants/arc/DP15104212
http://purl.org/au-research/grants/nhmrc/1122825
http://purl.org/au-research/grants/nhmrc/1032738
Appears in Collections:Aurora harvest 8
Physics publications

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