Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/133417
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Type: Journal article
Title: The effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study
Author: Tanner, M.S.
De Guingand, D.
Reddy, M.
Rowson, S.
Rolnik, D.L.
Da Silva Costa, F.
Davey, M.A.
Mol, B.W.
Wallace, E.M.
Palmer, K.R.
Citation: Hypertension in Pregnancy, 2021; 1-10
Publisher: Informa UK Limited
Issue Date: 2021
ISSN: 1064-1955
1525-6065
Statement of
Responsibility: 
Michael S. Tanner, Deborah De Guingand, Maya Reddy, Saskia Rowson, Daniel L. Rolnik, Fabricio Da Silva Costa, Mary-Ann Davey, Ben W. Mol, Euan M. Wallace, and Kirsten R. Palmer
Abstract: Objective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia. Methods:A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes. Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications. Conclusion:Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.
Keywords: Preeclampsia; hypertension; angiogenic; complications; comorbidities
Description: Online Publ
Rights: © 2021 Informa UK Limited, trading as Taylor & Francis Group
DOI: 10.1080/10641955.2021.1991371
Grant ID: http://purl.org/au-research/grants/nhmrc/1113902
Appears in Collections:Medicine publications

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