Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/136119
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Type: | Journal article |
Title: | Multi-layered ZIF-coated cells for the release of bioactive molecules in hostile environments |
Author: | Gan, L. Velásquez-Hernández, M.D.J. Emmerstorfer-Augustin, A. Wied, P. Wolinski, H. Zilio, S.D. Solomon, M. Liang, W. Doonan, C. Falcaro, P. |
Citation: | Chemical Communications, 2022; 58(72):10004-10007 |
Publisher: | Royal Society of Chemistry (RSC) |
Issue Date: | 2022 |
ISSN: | 1359-7345 1364-548X |
Statement of Responsibility: | Lei Gan, Miriam de J. Velásquez-Hernández, Anita Emmerstorfer-Augustin, Peter Wied, Heimo Wolinski, Simone Dal Zilio, Marcello Solomon, Weibin Liang, Christian Doonan, and Paolo Falcaro |
Abstract: | Metal-organic framework (MOF) coatings on cells enhance viability in cytotoxic environments. Here, we show how protective multi-layered MOF bio-composite shells on a model cell system (yeast) enhance the proliferation of living cells exposed to hostile protease-rich environments via the dissolution of the shells and release of a protease inhibitor (antitrypsin). |
Keywords: | Antineoplastic Agents Cell Survival Metal-Organic Frameworks |
Description: | Published on 01 August 2022 |
Rights: | This journal is © The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given. |
DOI: | 10.1039/d2cc03072a |
Grant ID: | http://purl.org/au-research/grants/arc/DP200102411 |
Published version: | http://dx.doi.org/10.1039/d2cc03072a |
Appears in Collections: | Chemistry and Physics publications |
Files in This Item:
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hdl_136119.pdf | Published version | 792.88 kB | Adobe PDF | View/Open |
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