Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/17508
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dc.contributor.authorThompson, E.-
dc.contributor.authorDragovic, R.-
dc.contributor.authorStephenson, S.-
dc.contributor.authorEccles, D.-
dc.contributor.authorCampbell, I.-
dc.contributor.authorDobrovic, A.-
dc.date.issued2005-
dc.identifier.citationBMC Cancer, 2005; 5(43):1-6-
dc.identifier.issn1471-2407-
dc.identifier.issn1471-2407-
dc.identifier.urihttp://hdl.handle.net/2440/17508-
dc.descriptionThe electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2407/5/43-
dc.description.abstractThe FANCA gene is one of the genes in which mutations lead to Fanconi anaemia, a rare autosomal recessive disorder characterised by congenital abnormalities, bone marrow failure, and predisposition to malignancy. FANCA is also a potential breast and ovarian cancer susceptibility gene. A novel allele was identified which has a tandem duplication of a 13 base pair sequence in the promoter region.-
dc.description.statementofresponsibilityElla Thompson, Rebecca L Dragovic, Sally-Anne Stephenson, Diana M Eccles, Ian G Campbell and Alexander Dobrovic-
dc.language.isoen-
dc.publisherBioMed Central Ltd.-
dc.rights© 2005 Thompson et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.-
dc.subjectHumans-
dc.subjectBreast Neoplasms-
dc.subjectOvarian Neoplasms-
dc.subjectGenetic Predisposition to Disease-
dc.subjectRisk-
dc.subjectGene Duplication-
dc.subjectGenotype-
dc.subjectPolymorphism, Genetic-
dc.subjectPolymorphism, Single-Stranded Conformational-
dc.subjectAlleles-
dc.subjectModels, Genetic-
dc.subjectAdult-
dc.subjectAged-
dc.subjectMiddle Aged-
dc.subjectFemale-
dc.subjectFanconi Anemia Complementation Group A Protein-
dc.subjectPromoter Regions, Genetic-
dc.subjectGenetic Variation-
dc.titleA novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer-
dc.typeJournal article-
dc.identifier.doi10.1186/1471-2407-5-43-
pubs.publication-statusPublished-
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