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Type: Thesis
Title: Studies of endothelial and leukocyte cell adhesion molecules in renal transplantation / by Warwick L. Grooby.
Author: Grooby, Warwick L.
Issue Date: 1996
School/Discipline: Dept. of Medicine
Abstract: This thesis examines the expression of cell adhesion molecules on both endothelial cells (ECs) and circulating leukocytes, and investigates the role of these molecules in renal allograft rejection. The aims of the study are to establish an ovine model of renal allograft transplantation, to generate monoclonal antibodies (mAbs) against ovine endothelial cell adhesion molecules, to examine the efficacy of the mAbs in prolonging the survival of the sheep renal allografts and to study the kinetics of expression of cell adhesion molecules (CAMs) during cellular activation 'in vitro' and 'in vivo' during the onset of allograft rejection.
Dissertation Note: Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1996
Subject: Cell adhesion molecules.
Kidneys Transplantation.
Description: Erratum is pasted on back end paper.
Bibliography: leaves 231-268.
xv, 268 leaves : ill. (chiefly col.) ; 30 cm.
Provenance: This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at:
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