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Type: Thesis
Title: Transcriptional analysis of the role of CD8+ T lymphocytes in acute neural herpes simplex virus infection / David C. Tscharke.
Author: Tscharke, David C.
Issue Date: 1997
School/Discipline: Dept. of Microbiology and Immunology
Abstract: The aim of this thesis is to analyse the molecular events associated with CD8+ T lymphocyte activity in HSV infected sensory ganglia. The role of CD8+ T cells in cytokine responses to ganglionic HSV infection is investigated, with particular reference to the Th1/Th2 paradigm and a known anti-viral mediator, IFN-[gamma]. A non-directed method of mRNA analysis is applied to HSV infected ganglia with the specific aim of identifying transcripts that may be associated with CD8+ T cell activity in the nervous system.
Dissertation Note: Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1997
Subject: Herpes simplex virus.
T cells.
Messenger RNA.
Ganglia, Sensory.
Mice as laboratory animals.
Description: Bibliography: leaves 141-182.
xi, 182, [36] leaves, [12] leaves of plates : ill. ; 30 cm.
Provenance: This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at:
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