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Type: Thesis
Title: Studies of cytokines in alloimmune responses / by Guy M. Patrick.
Author: Patrick, Guy M.
Issue Date: 1998
School/Discipline: Dept. of Medicine
Abstract: Analyses the cytokine gene expression and the manipulation of these responses in order to offer some insights into the Th1 and Th2 responses associated with allograft rejection. Supports the concept that the unmodified alloimmune response involves complex interactions between Th1-like, Th2-like and APC-derived cytokines. Immunomodulation of the alloimmune response is associated with the down regulation of multiple cytokines within both Th1 and Th2 populations with concurrent upregulation of IL-10 expression.
Dissertation Note: Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1998?
Subject: Immunosuppression.
Graft rejection.
Description: Bibliography: leaves 206-254.
xiii, 254 leaves : ill. (chiefly col.) ; 30 cm.
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