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Type: Journal article
Title: Hepatectomy for metastatic noncolorectal gastrointestinal, breast and testicular tumours
Author: Metcalfe, M.
Mullin, E.
Maddern, G.
Citation: Australian and New Zealand Journal of Surgery, 2006; 76(4):246-250
Publisher: Blackwell Science Asia
Issue Date: 2006
ISSN: 1445-1433
Statement of
Matthew S. Metcalfe, Emma J. Mullin and Guy J. Maddern
Abstract: Background: The indications for hepatectomy for colorectal or neuroendocrine metastases are becoming clear with increasing experience reported. For other primary diseases, however, the overall number of cases is relatively small, and it is more difficult to derive clear guidelines. This paper reviews the reported experience of hepatectomy for metastases from non-colorectal gastrointestinal primary cancers, breast cancer and testicular teratoma. The aim is to determine for each whether and under what circumstances hepatectomy is indicated. Methods: A Medline search was used to identify papers reporting hepatectomy for metastases from non-colorectal gastrointestinal carcinomas, breast carcinomas and testicular teratomas. The data collected included the primary disease, the number of cases reported, the survival post-hepatectomy and any prognostic factors associated with outcome. Results: Of the gastrointestinal malignancies, hepatectomy for gastric metastases yields a 5-year survival, roughly half that reported for colorectal disease, and further elucidation of prognostic factors would be desirable. Results were poor for other gastrointestinal malignancies. Good results were reported for breast and testicular teratoma. Conclusion: Of the non-colorectal gastrointestinal primaries, at present only hepatectomy for gastric metastases can be cautiously recommended. For nongastrointestinal primaries, hepatic metastases probably represent widespread dissemination even if occult, and therefore, hepatectomy may only be of use when effective adjuvant treatments are available.
Keywords: Breast; gastrointestinal; hepatectomy; metastasis; sarcoma; teratoma
Description: The definitive version is available at
RMID: 0020060433
DOI: 10.1111/j.1445-2197.2006.03689.x
Appears in Collections:Surgery publications

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