Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Hansemann, Boveri, chromosomes and the gametogenesis-related theories of tumours
Author: Bignold, L.
Coghlan, B.
Jersmann, H.
Citation: Cell Biology International, 2006; 30(7):640-644
Publisher: Academic Press Ltd
Issue Date: 2006
ISSN: 1065-6995
Abstract: Theodor Boveri (1862–1915) is often credited with suggesting (in 1914) the first chromosomal theory of cancer, especially in terms of abnormal numbers of chromosomes arising in cells by multipolar mitoses in adult cells. However, multipolar mitoses in animal cells had been described as early as 1875, and Hansemann (1858–1920), in publications between 1890 and 1919, included this mechanism among various ways by which abnormal chromosome numbers might arise in cells and cause tumour formation. Both theories were conceived in a period when gametogenic ideas of tumour formation were current. Boveri based his theory on the observation that some cells in early sea urchin embryos having abnormal chromosome complements wander from their usual developmental paths. His observation may have been seen by other authors at the time as support for Cohnheim's “embryonic cell rest” theory of cancer. Hansemann's contribution is seen as both the original, and the more significant of the chromosomal theories of cancer.
Keywords: aneuploidy
Description: Copyright © 2006 International Federation for Cell Biology
DOI: 10.1016/j.cellbi.2006.04.002
Description (link):
Appears in Collections:Aurora harvest 2
Paediatrics publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.