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dc.contributor.authorMickan, S.en
dc.contributor.authorMenikh, A.en
dc.contributor.authorLiu, H.en
dc.contributor.authorMannella, C.en
dc.contributor.authorMacColl, R.en
dc.contributor.authorAbbott, D.en
dc.contributor.authorMunch, J.en
dc.contributor.authorZhang, X.en
dc.identifier.citationPhysics in Medicine and Biology, 2002; 47(21):3789-3795en
dc.description© 2002 IOP Publishingen
dc.description.abstractWe report the first use of differential terahertz time-domain spectroscopy for bioaffinity sensing. Binding is observed by measuring the transmission of a thin layer of biotin bound to the sensor protein avidin. We demonstrate the THz wave transmission of a sub-micron-thick film and sensitivity to 0.1 µg cm−2 of biotin. These results point the way for a host of biosensor applications using T-rays, or pulsed far-infrared (FIR) radiation.en
dc.description.statementofresponsibilitySamuel P Mickan, Abdellah Menikh, Haibo Liu, Carmen A Mannella, Robert MacColl, Derek Abbott, Jesper Munch and X-C Zhangen
dc.publisherIOP Publishing Ltden
dc.subjectMacromolecular Substances; Avidin; Affinity Labels; Membranes, Artificial; Sensitivity and Specificity; Refractometry; Spectrum Analysis; Biosensing Techniques; Protein Binding; Biotin; Electromagnetic Phenomena; Surface Properties; Microwaves; Equipment Designen
dc.titleLabel-free bioaffinity detection using terahertz technologyen
dc.typeJournal articleen
pubs.library.collectionElectrical and Electronic Engineering publicationsen
dc.identifier.orcidAbbott, D. [0000-0002-0945-2674]en
Appears in Collections:Electrical and Electronic Engineering publications
Physics publications
Environment Institute publications

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