Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/27551
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Type: Journal article
Title: A comparison of estradiol levels between women with a hysterectomy and ovarian conservation and women with an intact uterus
Author: Simpson, J.
MacInnis, R.
English, D.
Gertig, D.
Morris, H.
Giles, G.
Citation: Climacteric, 2005; 8(3):300-303
Publisher: Parthenon Publishing Group
Issue Date: 2005
ISSN: 1369-7137
1473-0804
Abstract: OBJECTIVES: To compare the distribution of estradiol levels between women with a hysterectomy and ovarian conservation and women with an intact uterus. METHODS: A large cross-sectional study of women aged between 40 and 69 years, residing in Melbourne, Australia. Estradiol levels were available for 152 women with a hysterectomy and ovarian conservation and 1423 women with an intact uterus. All of the women were 'never-users' of hormone replacement therapy. RESULTS: For women under 55 years of age, we observed that those with a hysterectomy and ovarian conservation had slightly higher estradiol levels compared with those with an intact uterus after adjustment for age, body mass index, smoking status and alcohol intake (ratio of geometric means of estradiol levels = 1.24; 95% confidence interval = 1.00-1.53). For women who were 55 years or greater, the distribution of estradiol levels varied little by hysterectomy status. CONCLUSIONS: Our data do not suggest that women with hysterectomy and ovarian conservation have markedly different estradiol levels compared to women with an intact uterus.
Keywords: Humans; Estradiol; Hysterectomy; Prospective Studies; Cross-Sectional Studies; Age Distribution; Adult; Aged; Middle Aged; Female
RMID: 0020050958
DOI: 10.1080/13697130500186560
Appears in Collections:Molecular and Biomedical Science publications

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