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Type: Journal article
Title: The coagulation of insect hemolymph
Author: Theopold, Ulrich J.
Li, Dongmei
Fabbri, Marco
Scherfer, Christoph
Schmidt, Otto
Citation: Cellular and Molecular Life Sciences, 2002; 59(2):363-372
Publisher: Birkhauser Verlag Ag
Issue Date: 2002
ISSN: 1420-682X
School/Discipline: School of Agriculture, Food and Wine : Plant and Food Science
School of Agriculture, Food and Wine : Agricultural and Animal Science
Statement of
U. Theopold, D. Li, M. Fabbri, C. Scherfer and O. Schmidt
Abstract: In contrast to both vertebrates and non-insect arthropods, little is known about the coagulation of hemolymph (hemostasis) in insects. We discuss the integration of the hemostatic response with other branches of the insect immune system. We also describe the present stage in the characterization of both soluble and cellular factors that contribute to hemostasis in insects. The factors of the well-characterized clotting cascades of vertebrates, CMLS, Cell. Mol. Life Sci. 59 (2002) 363–372 1420-682X/02/020363-10 $ 1.50 + 0.20/0 © Birkhäuser Verlag, Basel, 2002 CMLS Cellular and Molecular Life Sciences primitive chelicerates and crustaceans are used to assess the implications of sequencing the whole Drosophila genome for searching candidate genes involved in hemostasis. Some striking similarities between blood clotting in vertebrates and the reaction of insect cells involved in hemolymph coagulation have implications for a phylogenetic comparison of hemostasis between divergent animal classes.
Keywords: Insect immunity; blood clotting; phosphatidylserine; phenoloxidase; coagulogen; transglutaminase; Drosophila melanogaster
Description: The original publication can be found at
Rights: © Birkhäuser Verlag, Basel, 2002
RMID: 0020021200
DOI: 10.1007/s00018-002-8428-4
Appears in Collections:Agriculture, Food and Wine publications

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