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Type: Journal article
Title: ARID proteins come in from the desert
Author: Kortschak, R.
Tucker, P.
Saint, R.
Citation: Trends in Biochemical Sciences, 2000; 25(6):294-299
Publisher: Elsevier Science London
Issue Date: 2000
ISSN: 0968-0004
Organisation: Centre for the Molecular Genetics of Development
Statement of
R. Daniel Kortschak, Philip W. Tucker and Robert Saint
Abstract: Members of the recently discovered ARID (AT-rich interaction domain) family of DNA-binding proteins are found in fungi and invertebrate and vertebrate metazoans. ARID-encoding genes are involved in a variety of biological processes including embryonic development, cell lineage gene regulation and cell cycle control. Although the specific roles of this domain and of ARID-containing proteins in transcriptional regulation are yet to be elucidated, they include both positive and negative transcriptional regulation and a likely involvement in the modification of chromatin structure.
Keywords: DNA-binding protein
Transcription factor
Description: Copyright © 2000 Elsevier Science Ltd. All rights reserved.
DOI: 10.1016/S0968-0004(00)01597-8
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Appears in Collections:Aurora harvest 6
Centre for the Molecular Genetics of Development publications
Molecular and Biomedical Science publications

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