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Type: Conference paper
Title: Gene network analysis and design
Author: Berryman, M.
Allison, A.
Abbott, D.
Citation: Biomedical applications of micro- and nanoengineering II : 13-15 December 2004, Sydney, Australia / Dan V. Nicolau (ed.), pp. 126-133
Publisher: SPIE
Publisher Place: Bellingham, Washington
Issue Date: 2005
Series/Report no.: Proceedings of SPIE--the International Society for Optical Engineering ; 5651.
ISBN: 081945611X
ISSN: 1605-7422
Conference Name: Biomedical Applications of Micro- and Nanoengineering (2nd : 2004 : Sydney, Australia)
Editor: Nicolau, D.
Statement of
Matthew J. Berryman, Andrew Allison, and Derek Abbott
Abstract: Gene networks are composed of many different interacting genes and gene products (RNAs and proteins). They can be thought of as switching regions in n-dimensional space or as mass-balanced signaling networks. Both approaches allow for describing gene networks with the limited quantitative or even qualitative data available. We show how these approaches can be used in modeling the apoptosis gene network that has a vital role in tumor development. The open question is whether engineering changes to this network could be used as a possible cancer treatment.
Description: © 2005 COPYRIGHT SPIE--The International Society for Optical Engineering
DOI: 10.1117/12.582096
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Appears in Collections:Aurora harvest 2
Electrical and Electronic Engineering publications

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