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Type: Conference paper
Title: Terahertz spectroscopy of bound water in nano suspensions
Author: Mickan, S.
Dordick, J.
Munch, J.
Abbott, D.
Zhang, X.
Citation: Biomedical applications of micro- and nanoengineering, 16-18 December 2002 / Dan V. Nicolau, Abraham P. Lee (eds.): pp. 49-61
Publisher: SPIE
Publisher Place: CDROM
Issue Date: 2002
Series/Report no.: Proceedings of SPIE--the International Society for Optical Engineering ; 4937
ISBN: 0-8194-4732-3
ISSN: 0277-786X
Conference Name: International Symposium on Smart Materials, Nano- and Micro-Smart Systems (2002 : Melbourne, Australia)
Editor: Nicolau, D.V.
Lee, A.P.
Statement of
Samuel P. Mickan, Jonathon Dordick, Jesper Munch, Derek Abbott, and Xi-Cheng Zhang
Abstract: The study of enzymatic protein molecules using terahertz time-domain spectroscopy (THz-TDS) has the potential to reveal molecular activity in real time without the use of labelling. Molecular hydration, or bound water, is a critical parameter in enzyme activity and THz-TDS measurements. For the first time we experimentally measure the terahertz-frequency response of nano-sized particles of protein and their level of molecular hydration. These measurements are valuable in understanding the terahertz response of biological systems and in studying the interaction between bound water and proteins.
Description: © 2003 COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
DOI: 10.1117/12.477384
Appears in Collections:Aurora harvest 2
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