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|Title:||Shiga toxin 'goes retro' in human primary kidney cells|
|Citation:||Kidney International, 2006; 70(12):2049-2051|
|Publisher:||Blackwell Publishing Inc|
|J C Paton and A W Paton|
|Abstract:||The pathway and the efficiency of intracellular trafficking of Shiga toxin differ between cell types, and this impacts on susceptibility to cytotoxicity. Warnier et al. demonstrate that in cell types targeted during human disease, Shiga toxin undergoes retrograde transport via the trans-Golgi network to the endoplasmic reticulum, albeit less efficiently than in HeLa cells.|
|Description:||© 2007 International Society of Nephrology|
|Appears in Collections:||Aurora harvest 6|
Molecular and Biomedical Science publications
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