Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/34823
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DC Field | Value | Language |
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dc.contributor.author | Toder, R. | - |
dc.contributor.author | Grutzner, F. | - |
dc.contributor.author | Haaf, T. | - |
dc.contributor.author | Bausch, E. | - |
dc.date.issued | 2001 | - |
dc.identifier.citation | Chromosome Research: the international journal for all aspects of chromosome and nuclear biology, 2001; 9(6):431-435 | - |
dc.identifier.issn | 0967-3849 | - |
dc.identifier.issn | 1573-6849 | - |
dc.identifier.uri | http://hdl.handle.net/2440/34823 | - |
dc.description | The original publication can be found at www.springerlink.com | - |
dc.description.abstract | DNA sequencing reveals that the genomes of the human, gorilla and chimpanzee share more than 98% homology. Comparative chromosome painting and gene mapping have demonstrated that only a few rearrangements of a putative ancestral mammalian genome occurred during great ape and human evolution. However, interspecies representational difference analysis (RDA) of the gorilla between human and gorilla revealed gorilla-specific DNA sequences. Cloning and sequencing of gorilla-specific DNA sequences indicate that there are repetitive elements. Gorilla-specific DNA sequences were mapped by fluorescence in-situ hybridization (FISH) to the subcentromeric/centromeric regions of three pairs of gorilla submetacentric chromosomes. These sequences could represent either ancient sequences that got lost in other species, such as human and orang-utan, or, more likely, recent sequences which evolved or originated specifically in the gorilla genome. | - |
dc.description.statementofresponsibility | R. Toder, F. Grützner, T. Haaf, E. Bausch | - |
dc.language.iso | en | - |
dc.publisher | Kluwer Academic Publ | - |
dc.source.uri | http://dx.doi.org/10.1023/a:1011605824530 | - |
dc.subject | genome evolution - species-specific DNA sequences | - |
dc.title | Species-specific evolution of repeated DNA sequences in great apes | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1023/A:1011605824530 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Grutzner, F. [0000-0002-3088-7314] | - |
Appears in Collections: | Aurora harvest Environment Institute Leaders publications Molecular and Biomedical Science publications |
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