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https://hdl.handle.net/2440/35684
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Type: | Journal article |
Title: | The FEV1/FEV6 ratio is a good substitute for the FEV1/FVC ration in the elderly |
Author: | Melbye, H. Medbo, A. Crockett, A. |
Citation: | Primary Care Respiratory Journal, 2006; 15(5):294-298 |
Publisher: | Strategic Medical Publishing |
Issue Date: | 2006 |
ISSN: | 1471-4418 1475-1534 |
Statement of Responsibility: | Hasse Melbye, Astri Medbø and Alan Crockett |
Abstract: | <h4>Aims</h4>To determine the agreement between the FEV1/FEV6 ratio and the FEV1/FVC ratio in an elderly population.<h4>Method</h4>The study sample consisted of 3874 participants in a cross-sectional population survey in Tromsö, Norway, aged 60 years or more, in whom acceptable spirometry had been obtained. Mean differences between the FEV1/FEV6 ratio (%) and the FEV1/FVC ratio (%) were calculated according to age, sex, smoking habit, and the degree of airflow limitation. ROC-curve analysis and Kappa-statistics were used to estimate the utility of the FEV1/FEV6 ratio in predicting an FEV1/FVC ratio < 70%.<h4>Results</h4>The mean difference between FEV1/FEV6% and FEV1/FVC% was 2.7% in both men and women. The difference between the two measures increased somewhat with increasing age, and was more pronounced with smoking and decreasing FEV1/FVC ratio. The value for the FEV1/FEV6 ratio which best predicted an FEV1/FVC ratio of 70%, was 73%, and a very good agreement was found between these two cut-off values (kappa = 0.86).<h4>Conclusion</h4>The FEV1/FEV6 ratio appears to be a good substitute for the FEV1/FVC ratio in an elderly population. |
Keywords: | Spirometry primary care FEV1 FEV6 FVC |
Rights: | © Elsevier |
DOI: | 10.1016/j.pcrj.2006.07.002 |
Published version: | http://www.thepcrj.org/journ/view_article.php?article_id=180&volissue=16 |
Appears in Collections: | Aurora harvest 6 General Practice publications |
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