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Type: Journal article
Title: Pharmacokinetic studies in migraine: What questions should physicians ask?
Author: Rolan, P.
Citation: Current Pain and Headache Reports, 2004; 8(3):219-222
Publisher: Current Science Inc.
Issue Date: 2004
ISSN: 1531-3433
Abstract: Migraine is a benign self-limiting condition for which the objective of treatment is to maximize the patient’s quality of life by reducing the frequency of attacks and attenuating the pain and suffering of an individual attack as quickly and safely as possible. Evaluating the efficacy of antimigraine treatments, particularly those for the management of the acute attack, is relatively easy because acute symptomatic benefit is the criterion of success. For prophylaxis, therapeutic success generally is measured by relatively simple parameters such as attack frequency. Given that the clinical response to antimigraine therapies relatively is readily assessed by history, the role of more sophisticated investigations such as pharmacokinetic studies may not be immediately clear. This paper aims to provide clinicians with a guide to interpretation of such studies.
Keywords: Migraine; pharmacokinetics
Description: Copyright © 2004 by Current Science Inc.
RMID: 0020065995
DOI: 10.1007/s11916-004-0055-3
Appears in Collections:Pharmacology publications

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