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|Non-invasive determination of myocardial oxygen consumption with ¹¹C-acetate and positron emission tomography
|Brown, Michael A., 1954-
|Dept. of Medicine
|Assessment of myocardial metabolism with radiolabelled substrates and positron emission tomography provides a potentially sensitive technique to investigate physiological and pathological cardiac states "in vitro". Prior studies have indicated that overall metabolic activity cannot be estimated from rates of utilization of any one particular substrate. It was hypothesized that acetate labelled with carbon-11 would provide an index of oxidative metabolism, based on fundamental biochemical principles. The hypothesis is confirmed in studies using isolated perfused rabbit hearts and closed chest canine studies.
|Thesis (M.D.) -- University of Adelaide, Dept. of Medicine, 1995
|Heart Radionuclide imaging; Tomography, Emission; Positrons Emission; Myocardium Diseases; Heart Metabolism Disorders
|Bibliography: leaves 94-106.
v, 106,  leaves,  leaves of plates
|This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals
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