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Type: Thesis
Title: Assessment of CD44 and K19 as markers for circulating breast cancer cells using immunobead RT-PCR
Author: Eaton, Michael Campbell
Issue Date: 1997
School/Discipline: Dept. of Medicine
Abstract: This thesis presents the development of an assay for reverse transcription-polymerase chain reaction (RT-PCR) to be applied to the immunomagnetic isolation of carcinoma cells, as a possible means of detecting small numbers of breast cancer cells in a haemopoietic environment. The messenger RNA expression of two different genes, CD44 and the cytokeratin K19, is assessed for suitability as tumour markers for the Immunobead RT-PCR method, and clinical results using K19 are presented.
Dissertation Note: Thesis (M.D.) -- University of Adelaide, Dept. of Medicine, 1997?
Subject: Breast Cancer Molecular diagnosis; Tumor markers Diagnostic use; Breast Tumors Diagnosis; Immunoglobulins; Polymerase chain reaction
Description: Includes bibliographies.
[xvii], 173, [38] leaves, [18] leaves of plates
Provenance: This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at:
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