Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/39099
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Type: Journal article
Title: Phased-array intracardiac echocardiography for defining cavotricuspid isthmus anatomy during radiofrequency ablation of typical atrial flutter
Author: Morton, J.
Sanders, P.
Davidson, N.
Sparks, P.
Vohra, J.
Kalman, J.
Citation: Journal of Cardiovascular Electrophysiology, 2003; 14(6):591-597
Publisher: Futura Publ Co
Issue Date: 2003
ISSN: 1045-3873
1540-8167
Statement of
Responsibility: 
Joseph B. Morton, Prashanthan Sanders, Neil C. Davidson, Paul B. Sparks, Jitendra K. Vohra, Jonathan M. Kalman
Abstract: INTRODUCTION:Cavotricuspid isthmus (CTI) topography includes ridges, pouches, recesses, and trabeculations. These features may limit the success of radiofrequency ablation (RFA) of typical atrial flutter (AFL). The aim of this study was to assess the utility of phased-array intracardiac echocardiography (ICE) for imaging the CTI and monitoring RFA of AFL. METHODS AND RESULTS:Fifteen patients (mean age 64 +/- 9 years) underwent ICE assessment (imaging frequency 7.5-10 MHz) before and after RFA of AFL. The ICE catheter was positioned at the inferior vena cava-right atrial junction and the following parameters were measured: (1) CTI length from the tricuspid valve to the eustachian ridge; (2) extent of CTI pouching; and (3) thickness pre/post RFA of the anterior, mid, and posterior CTI. CTI length was 35 +/- 6 mm at end-ventricular systole but shorter (30 +/- 6 mm) and more pouched at end-ventricular diastole (P = 0.02). A pouch or recess was seen in 11 of 15 patients (mean depth 6 +/- 2 mm). The septal CTI was more pouched than the lateral CTI, but the latter had more prominent trabeculations. Trabeculations were seen in 10 of 15 patients, and at these locations the CTI was 4.6 +/- 1 mm thick. Anterior, mid, and posterior CTI thickness pre-RFA was 4.1 +/- 0.8, 3.3 +/- 0.5, and 2.7 +/- 0.9 mm, respectively (P < 0.001 by analysis of variance). ICE guided RFA away from unfavorable CTI features (recesses/thick trabeculations). RFA applications created discrete CTI lesions that coalesced, forming diffuse CTI swelling. Post-RFA thickness was as follows: anterior 4.8 +/- 0.8 mm (P = NS vs pre); mid 3.8 +/- 0.8 mm (P = 0.05 vs pre); and posterior 3.8 +/- 0.8 mm (P = 0.02 vs pre). CONCLUSION:Phased-array ICE permits novel real-time CTI imaging with excellent endocardial resolution and may facilitate RFA of AFL.
Keywords: intracardiac echocardiography; atrial flutter; radiofrequency ablation; cavotricuspid isthmus
Description: The definitive version is available at www.blackwell-synergy.com
RMID: 0020071954
DOI: 10.1046/j.1540-8167.2003.02152.x
Published version: http://www.blackwell-synergy.com/doi/abs/10.1046/j.1540-8167.2003.02152.x
Appears in Collections:Medicine publications

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