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https://hdl.handle.net/2440/39703
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dc.contributor.author | Robinson, B. | - |
dc.contributor.author | Fletcher, J. | - |
dc.contributor.author | Richardson, A. | - |
dc.contributor.author | Tomlinson, P. | - |
dc.contributor.author | Bell, R. | - |
dc.contributor.author | Fisher, C. | - |
dc.contributor.author | Condous, M. | - |
dc.contributor.author | Ventura, R. | - |
dc.contributor.author | Scott, A. | - |
dc.contributor.author | Stary, D. | - |
dc.contributor.author | Allen, R. | - |
dc.contributor.author | Lippey, E. | - |
dc.contributor.author | Appleberg, M. | - |
dc.contributor.author | Chao, A. | - |
dc.contributor.author | Fitridge, R. | - |
dc.contributor.author | Frydman, G. | - |
dc.contributor.author | Hazelton, S. | - |
dc.contributor.author | King, B. | - |
dc.contributor.author | Middleton, P. | - |
dc.contributor.author | Pai, P. | - |
dc.contributor.author | et al. | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | ANZ Journal of Surgery, 2003; 73(3):95-99 | - |
dc.identifier.issn | 1445-1433 | - |
dc.identifier.issn | 1445-2197 | - |
dc.identifier.uri | http://hdl.handle.net/2440/39703 | - |
dc.description.abstract | This trial was designed to compare graft patency between expanded polytetrafluoroethylene (PTFE) and fluoropolymer coated Dacron for femoropopliteal bypass in patients in whom saphenous vein was unavailable. Methods: A multicentre prospective trial randomized 129 patients (74 men, 55 women) who underwent femoropopliteal bypass using either a PTFE or fluoropolymer coated Dacron graft. The indication for operation was disabling claudication in 68 (52.7%) and critical limb ischaemia in 61 (47.3%) patients. Distal anastomosis was above the knee in 76 (58.9%) and below the knee in 53 (41.1%) patients. Results: Primary patency at 6, 12 and 24 months was 71%, 56% and 47% for PTFE and 50%, 36% and 36% for fluoropolymer coated Dacron (P = 0.002), respectively. Secondary patency at 6, 12 and 24 months was 77%, 60% and 48% for PTFE and 66%, 49% and 46% for fluoropolymer coated Dacron (P = 0.13), respectively. The superior primary patency of PTFE over fluoropolymer coated Dacron was most evident in patients with poor prognostic indicators for graft survival: critical limb ischaemia (P = 0.001); below-knee anastomosis (P = 0.01); and smaller (6 mm) diameter grafts (P = 0.002). Graft thrombosis developed in the first month in 22 of 61 (36%) patients receiving fluoropolymer coated grafts compared to six of 68 (8.8%) patients receiving PTFE, which accounts for the difference in primary patency. Successful thrombectomy in 10 of the 22 fluoropolymer coated grafts resulted in similar secondary patency. Conclusion: Polytetrafluoroethylene has superior primary patency and similar secondary patency to fluoropolymer coated Dacron. These results support the preferential use of PTFE in patients with critical limb ischaemia, especially when a below-knee distal anastomosis and smaller diameter graft is required. | - |
dc.description.statementofresponsibility | A. Richardson, P. Tomlinson, R. Bell, C. Fisher, M. Condous, R. Ventura, A. Scott, D. Stary, R. Allen, E. Lippey, M. Appleberg, A. Chao, R. Fitridge, G. Frydman, S. Hazelton, B. King, P. Middleton, P. Pai, I. Thomson, B. Beiles, A. Gray-Wheale and R. Lane | - |
dc.language.iso | en | - |
dc.publisher | Blackwell Science Asia | - |
dc.source.uri | http://dx.doi.org/10.1046/j.1445-2197.2003.02653.x | - |
dc.subject | Australian and New Zealand Femoropopliteal Graft Trial Participants | - |
dc.subject | Leg | - |
dc.subject | Femoral Artery | - |
dc.subject | Popliteal Artery | - |
dc.subject | Humans | - |
dc.subject | Intermittent Claudication | - |
dc.subject | Ischemia | - |
dc.subject | Fluorocarbon Polymers | - |
dc.subject | Polytetrafluoroethylene | - |
dc.subject | Polyethylene Terephthalates | - |
dc.subject | Coated Materials, Biocompatible | - |
dc.subject | Blood Vessel Prosthesis Implantation | - |
dc.subject | Prospective Studies | - |
dc.subject | Vascular Patency | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Outcome Assessment, Health Care | - |
dc.title | Fluoropolymer coated Dacron or polytetrafluoroethylene for femoropopliteal bypass grafting: a multicentre trial | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1046/j.1445-2197.2003.02653.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Fitridge, R. [0000-0001-6258-5997] | - |
Appears in Collections: | Aurora harvest Surgery publications |
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