Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/39881
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Type: Journal article
Title: Hormone replacement therapy: where to now?
Author: MacLennan, A.
Citation: Australian Prescriber, 2003; 26(1):8-10
Publisher: Australian Prescriber
Issue Date: 2003
ISSN: 0312-8008
1839-3942
Statement of
Responsibility: 
Alastair H. MacLennan
Abstract: The Women's Health Initiative Study was stopped because of safety concerns about hormone replacement therapy with oestrogen and progestogen. There was an increase in breast cancer, however this was not greater than the increase reported in observational studies. Although there was an increase in vascular events, many of the women in the study had pre-existing risk factors for cardiovascular disease. No long-term trials of combined hormone replacement therapy are continuing, so the balance between benefit and harm will remain uncertain. Hormone replacement therapy can still be prescribed for menopausal symptoms and for osteoporosis prevention, but the need for continued use should be reviewed annually.
Keywords: menopause; breast cancer; heart disease
Description: Copyright © 2003 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.
RMID: 0020072610
DOI: 10.18773/austprescr.2003.006
Published version: http://www.australianprescriber.com/magazine/26/1/8/10/
Appears in Collections:Obstetrics and Gynaecology publications

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