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https://hdl.handle.net/2440/42274
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Type: | Journal article |
Title: | The use of a “Liquid” electrode in hepatic electrolysis |
Author: | Finch, G. Fosh, B. Anthony, A. Texler, M. Pearson, S. Dennison, A. Maddern, G. |
Citation: | Journal of Surgical Research, 2004; 120(2):272-277 |
Publisher: | Academic Press Inc Elsevier Science |
Issue Date: | 2004 |
ISSN: | 0022-4804 1095-8673 |
Statement of Responsibility: | J. Guy Finch, Beverley G. Fosh, Adrian A. Anthony, Michael Texler, Susan Pearson, Ashley R. Dennison and Guy J. Maddern |
Abstract: | Background: The use of direct current electrolysis as a local nonthermal ablative technique for colorectal liver metastases promises to be a simple, safe, and effective therapy. Under general anesthesia, electrolysis is presently limited to tumors smaller than 5 cm, due to the protracted nature of its administration. In an attempt to enhance the effect of electrolysis, a direct current was passed through a preinjected bolus of acetic acid. Methods: The effect of a combination of electrolysis and an injection of acetic acid was tested in the liver of eight normal pigs. The volumes of necrosis caused were analyzed. Results: Acetic acid independently produced a volume of necrosis but did not provide a volumetric or rate advantage when used in combination with a direct current. Statistically, the only main effect on the volume of necrosis was a result of electrolysis. Conclusion: The use of 50% acetic acid to augment the efficacy of direct current electrolysis cannot be recommended. |
Keywords: | Acetic acid colorectal liver metastases electrochemical therapy electrolysis porcine model |
Description: | Copyright © 2004 Elsevier Inc. All rights reserved. |
DOI: | 10.1016/j.jss.2004.03.019 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/622901/description#description |
Published version: | http://dx.doi.org/10.1016/j.jss.2004.03.019 |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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