Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/43211
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Type: Journal article
Title: Quality of Cochrane reviews: assessment of sample from 1998
Author: Olsen, O.
Middleton, P.
Ezzo, J.
Gotzsche, P.
Hadhazy, V.
Herxheimer, A.
Kleijnen, J.
McIntosh, H.
Citation: British Medical Journal, 2001; 323(7317):829-832
Publisher: British Med Journal Publ Group
Issue Date: 2001
ISSN: 0959-535X
1756-1833
Statement of
Responsibility: 
Ole Olsen, Philippa Middleton, Jeanette Ezzo, Peter C Gøtzsche, Victoria Hadhazy, Andrew Herxheimer, Jos Kleijnen, Heather McIntosh,
Abstract: OBJECTIVE: To assess the quality of Cochrane reviews. DESIGN: Ten methodologists affiliated with the Cochrane Collaboration independently examined, in a semistructured way, the quality of reviews first published in 1998. Each review was assessed by two people; if one of them noted any major problems, they agreed on a common assessment. Predominant types of problem were categorised. SETTING: Cyberspace collaboration coordinated from the Nordic Cochrane Centre. STUDIES: All 53 reviews first published in issue 4 of the Cochrane Library in 1998. MAIN OUTCOME MEASURE: Proportion of reviews with various types of major problem. RESULTS: No problems or only minor ones were found in most reviews. Major problems were identified in 15 reviews (29%). The evidence did not fully support the conclusion in nine reviews (17%), the conduct or reporting was unsatisfactory in 12 reviews (23%), and stylistic problems were identified in 12 reviews (23%). The problematic conclusions all gave too favourable a picture of the experimental intervention. CONCLUSIONS: Cochrane reviews have previously been shown to be of higher quality and less biased on average than other systematic reviews, but improvement is always possible. The Cochrane Collaboration has taken steps to improve editorial processes and the quality of its reviews. Meanwhile, the Cochrane Library remains a key source of evidence about the effects of healthcare interventions. Its users should interpret reviews cautiously, particularly those with conclusions favouring experimental interventions and those with many typographical errors.
Keywords: Humans; Evidence-Based Medicine; Review Literature as Topic; Meta-Analysis as Topic; Databases as Topic; Bias
Description: © 2001 BMJ Publishing Group
RMID: 0020077144
DOI: 10.1136/bmj.323.7317.829
Appears in Collections:Obstetrics and Gynaecology publications

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