Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/43773
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Type: | Journal article |
Title: | Lifestyle impact and the biology of the human scrotum |
Author: | Ivell, R. |
Citation: | Reproductive Biology and Endocrinology, 2007; 5(15):1-8 |
Publisher: | Biomed Central Ltd. |
Issue Date: | 2007 |
ISSN: | 1477-7827 1477-7827 |
Statement of Responsibility: | Richard Ivell |
Abstract: | The possession of a scrotum to contain the male gonads is a characteristic feature of almost all mammals, and appears to have evolved to allow the testes and epididymis to be exposed to a temperature a few degrees below that of core body temperature. Analysis of cryptorchid patients, and those with varicocele suggest that mild scrotal warming can be detrimental to sperm production, partly by effects on the stem cell population, and partly by effects on later stages of spermatogenesis and sperm maturation. Recent studies on the effects of clothing and lifestyle emphasize that these can also lead to chronically elevated scrotal temperatures. In particular, the wearing of nappies by infants is a cause for concern in this regard. Together all of the evidence indirectly supports the view that lifestyle factors in addition to other genetic and environmental influences could be contributing to the secular trend in declining male reproductive parameters. The challenge will be to provide relevant and targeted experimental results to support or refute the currently circumstantial evidence. |
Keywords: | Scrotum Animals Humans Body Temperature Life Style Fertility Male |
Rights: | © 2007 Ivell; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
DOI: | 10.1186/1477-7827-5-15 |
Published version: | http://www.rbej.com/content/5/1/15 |
Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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hdl_43773.pdf | Published version | 797.92 kB | Adobe PDF | View/Open |
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