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Type: Journal article
Title: Synthesis and substitution reactions of N-protected 2-(phenylselenonylmethyl) pyrrolidines
Author: Cooper, M.
Ward, A.
Citation: Australian Journal of Chemistry, 1997; 50(3):181-187
Publisher: CSIRO Publishing
Issue Date: 1997
ISSN: 0004-9425
Abstract: <jats:p> Alkyl phenyl selenides derived from the benzeneselenenyl chloride induced cyclization of N-protected pent-4-enylamines can be converted in good yield into the corresponding 2-hydroxymethyl- or 2- alkoxymethyl-substituted pyrrolidines by oxidation to the corresponding selenone, followed by reaction with water (or hydroxide) or with the corresponding alcohol. Details of the reactions and possible mechanisms for the substitution are discussed.</jats:p>
RMID: 0030002705
DOI: 10.1071/C96148
Appears in Collections:Chemistry publications

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