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|Title:||Late-onset post-traumatic Phaeoacremonium parasiticum endophthalmitis|
|Citation:||Clinical and Experimental Ophthalmology, 2007; 35(4):366-368|
|Publisher:||Blackwell Publishing Asia|
|Tu Khai Huynh, Lawrence R Lee and David Ellis|
|Abstract:||This is the first documented case of Phaeoacremonium parasiticum endophthalmitis to the authors' knowledge. P. parasiticum has been described in the literature causing various skin, subcutaneous and joint infections and one case of infective endocarditis, but has never been documented as an ocular infectious agent. The most likely source of inoculation in this case was a penetrating injury caused by a stick 5 years prior to the presentation. An enucleation was avoided through treatment with intravitreal antibiotics and amphotericin and oral voriconazole, and the patient's vision stabilized at 6/18. Microbiological studies were delayed but confirmed the mould's sensitivity to amphotericin B and voriconazole.|
|Keywords:||Humans; Ascomycota; Endophthalmitis; Eye Infections, Fungal; Wound Infection; Mycoses; Eye Injuries, Penetrating; Amphotericin B; Triazoles; Pyrimidines; Antifungal Agents; Drug Therapy, Combination; Microbial Sensitivity Tests; Mycological Typing Techniques; Adult; Male; Voriconazole|
|Description:||The definitive version is available at www.blackwell-synergy.com|
|Appears in Collections:||Molecular and Biomedical Science publications|
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