Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/44489
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Trends in incidence of treated end-stage renal disease, overall and by primary renal disease, in persons aged 20-64 years in Europe, Canada and the Asia-Pacific region, 1998-2002 |
Author: | Stewart, J. McCredie, M. Williams, S. Jager, K. Trpeski, L. McDonald, S. |
Citation: | Nephrology, 2007; 12(5):520-527 |
Publisher: | Blackwell Publishing Asia |
Issue Date: | 2007 |
ISSN: | 1320-5358 1440-1797 |
Organisation: | ESRD Incidence Study |
Statement of Responsibility: | John H Stewart, Margaret RE McCredie, Sheila M Williams, Kitty J Jager, Lilyanna Trpeski, Stephen P McDonald, for the ESRD Incidence Study GROUP |
Abstract: | Aims: To determine if rates of diabetic and non-diabetic end-stage renal disease (ESRD), which had been rising in young and middle-aged adults in all populations up to the mid-1990s, had started to decline, and if so, whether improvement had occurred in respect of each of the principal primary renal diseases causing ESRD. Methods: Poisson regression of age- and sex-standardized incidence of ESRD for persons aged 20–64 years in 18 populations from Europe, Canada and the Asia-Pacific region, for 1998–2002. Results: In persons from 12 European descent (Europid) populations combined, there was a small downward trend in all-cause ESRD (−1.7% per year, P = 0.001), with type 1 diabetic ESRD falling by 7.8% per year (P < 0.001), glomerulonephritic ESRD by 3.1% per year (P = 0.001), and ‘all other non-diabetic’ ESRD by 2.5% per year (P = 0.02). The reductions in ESRD attributed to hypertensive (−2.2% per year) and polycystic renal disease (−1.5% per year) and unknown diagnosis (−0.2% per year) were not statistically significant. On the other hand, the incidence of type 2 diabetic ESRD rose by 9.9% per year (P < 0.001) in the combined Europid population, although that of (principally type 2) diabetic ESRD remained unchanged in the pooled data from the four non-Europid populations. Conclusion: Recent preventive strategies, probably chiefly modern renoprotective treatment, appear to have been effective for tertiary prevention of ESRD caused by the proteinuric nephropathies other than type 2 diabetic nephropathy, for which the continuing increase in Europid populations represents a failure of prevention and/or a change in the nephropathic potential of type 2 diabetes. |
Keywords: | ESRD Incidence Study Group Humans Polycystic Kidney Diseases Kidney Diseases Diabetic Nephropathies Kidney Failure, Chronic Glomerulonephritis Hypertension Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Incidence Poisson Distribution Age Distribution Adult Middle Aged Canada Asia Europe Pacific Islands |
Description: | The definitive version is available at www.blackwell-synergy.com |
DOI: | 10.1111/j.1440-1797.2007.00830.x |
Published version: | http://dx.doi.org/10.1111/j.1440-1797.2007.00830.x |
Appears in Collections: | Aurora harvest Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.