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Type: Journal article
Title: Intraorbital injection of triamcinolone acetonide in patients with idiopathic orbital inflammation
Author: Leibovitch, I.
Prabhakaran, V.
Davis, G.
Selva-Nayagam, D.
Citation: JAMA Ophthalmology, 2007; 125(12):1647-1651
Publisher: Amer Medical Assoc
Issue Date: 2007
ISSN: 0003-9950
Abstract: <h4>Objective</h4>To present findings of a pilot study on intraorbital corticosteroid therapy in the management of idiopathic orbital inflammation.<h4>Methods</h4>This prospective, noncomparative, interventional case series included patients with clinically, radiologically, and histologically confirmed idiopathic orbital inflammation with an anterior orbital mass. Twenty to 40 mg/mL of triamcinolone acetonide was injected intraorbitally (intralesionally or perilesionally) in all patients. The injection was repeated at 4-week intervals if complete resolution was not achieved. Patients were assessed for local and systemic complications of corticosteroid injection. Visual acuity, fundus examination, intraocular pressure, blood pressure, and serum glucose levels were measured at each visit.<h4>Results</h4>Ten patients (5 men and 5 women; mean age, 49.8 years [age range, 25-82 years]) received treatment. In 4 patients, an orbital mass was noted; in 6 patients, the lacrimal gland was involved (dacryoadenitis). Substantial improvement (1 patient) or complete resolution (8 patients) was noted during a follow-up of 9.8 months (range, 3-24 months).<h4>Conclusion</h4>Intraorbital injection of a corticosteroid is an effective treatment for idiopathic orbital inflammation and may be considered first-line treatment in selected patients.
Keywords: Orbit
Triamcinolone Acetonide
Tomography, X-Ray Computed
Magnetic Resonance Imaging
Prospective Studies
Pilot Projects
Visual Acuity
Aged, 80 and over
Middle Aged
Orbital Pseudotumor
Description: Copyright © 2007 American Medical Association. All Rights Reserved.
DOI: 10.1001/archopht.125.12.1647
Appears in Collections:Aurora harvest 6
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