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Type: Book chapter
Title: Fragile sites
Author: Sutherland, G.
Citation: Encyclopedia of Life Sciences, 2007 / Wiley, J., Sons (ed./s), pp.1-7
Publisher: Wiley
Publisher Place: UK
Issue Date: 2007
ISBN: 9780470066515
Abstract: Fragile sites are specific points on chromosomes that show nonrandom gaps or breaks when the cells from which the chromosomes have been prepared have been exposed to a specific chemical agent or condition of tissue culture. Hence a fragile site is an area of chromatin which is not compacted when viewed in mitosis.
Keywords: fragile X syndrome; Jacobsen syndrome; trinucleotide repeat; fragile site; FRAXA; FRAXE
Rights: © 1999-2008John Wiley & Sons, Inc.
RMID: 0020077487
DOI: 10.1002/9780470015902.a0005547.pub2
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Appears in Collections:Paediatrics publications

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