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dc.contributor.authorMartiniuk, A.en
dc.contributor.authorLee, C.en
dc.contributor.authorLawes, C.en
dc.contributor.authorUeshima, H.en
dc.contributor.authorSuh, I.en
dc.contributor.authorLam, T.en
dc.contributor.authorGu, D.en
dc.contributor.authorFeigin, V.en
dc.contributor.authorJamrozik, K.en
dc.contributor.authorOhkubo, T.en
dc.contributor.authorWoodward, M.en
dc.identifier.citationJournal of Hypertension, 2007; 25(1):73-79en
dc.descriptionCopyright © 2007, Lippincott Williams & Wilkinsen
dc.description.abstractOBJECTIVE: About half of the world's burden of cardiovascular disease is carried by countries in the Asia-Pacific region. This study aimed to quantify the contribution of hypertension to cardiovascular diseases (CVD) at the country level, by calculating the sex-specific, population-attributable fractions (PAFs) for fatal ischaemic heart disease (IHD) and stroke (haemorrhagic and ischaemic) for the World Health Organization Western Pacific and South-east Asian regions. METHODS: The most recent sex-specific prevalence data on hypertension were sought. Age-adjusted hazard ratio (HR) estimates for fatal IHD and stroke associated with hypertension were obtained using Cox analyses of individual participant cohort data from 600,000 adult participants in the Asia-Pacific Cohort Studies Collaboration. HR estimates and prevalence were then used to calculate sex-specific PAFs for fatal IHD and stroke, by country. RESULTS: In 15 countries with available data, the prevalence of hypertension ranged from 5-47% in men and from 7-38% in women. Overall, the fraction of IHD attributable to hypertension ranged from 4-28% in men and from 8-39% in women. Corresponding ranges for haemorrhagic stroke were 18-66% and 15-49%, and for ischaemic stroke were 8-44% and 12-45%. CONCLUSIONS: In the Asia-Pacific region, up to 66% of some subtypes of CVD can be attributed to hypertension, underscoring the immense impact that blood pressure- lowering strategies could have in this populous region.en
dc.description.statementofresponsibilityMartiniuk AL, Lee CM, Lawes CM, Ueshima H, Suh I, Lam TH, Gu D, Feigin V, Jamrozik K, Ohkubo T, Woodward M and Asia-Pacific Cohort Studies Collaborationen
dc.publisherLippincott Williams & Wilkinsen
dc.titleHypertension: Its prevalence and population-attributable fraction for mortality from cardiovascular disease in the Asia-Pacific regionen
dc.typeJournal articleen
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