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https://hdl.handle.net/2440/46952
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Type: | Journal article |
Title: | Temporal trends in the frequency and longer-term outcome of heart failure complicating myocardial infarction |
Author: | Najafi, F. Dobson, A. Hobbs, M. Jamrozik, K. |
Citation: | European Journal of Heart Failure, 2007; 9(9):879-885 |
Publisher: | Elsevier Science BV |
Issue Date: | 2007 |
ISSN: | 1388-9842 1879-0844 |
Abstract: | Aims To investigate trends in incidence and long-term outcome of heart failure (HF) developing within 28 days of first-ever acute myocardial infarction (AMI). Methods and results We identified all residents of Perth, Western Australia aged 25–64 years, with no history of HF, who experienced a non-fatal, first-ever AMI between 1984 and 1993, and followed them for ten years. All patients (N = 4006) met the criteria for ‘definite AMI’ in WHO MONItoring trends and determinants of CArdiovascular disease (MONICA) Project and 897 (22.4%) had early-onset HF complicating the index event. After adjustment for age, current smoking, history of diabetes and hypertension, Q-wave and anterior wall AMI, the odds of developing HF declined by 9% (odds ratio for period 1989–1993 relative to 1984–1988 = 0.91, 95% confidence interval (95%CI): 0.78 to 1.06). Over 10 years of follow-up, patients with early-onset HF had a cumulative average number of re-admissions of 28 per 100 as compared with 9 per 100 in patients without HF. After adjustment for age, history of diabetes and hypertension, the hazard of death in patients with early-onset HF declined by 26% (HR for the period 1989–1993 relative to 1984–1988 = 0.74, 95%CI: 0.57 to 0.96). Conclusion Our data suggest a decline in the incidence of, and show encouraging evidence of improvement in survival after, early-onset HF complicating AMI. |
Keywords: | Heart failure Myocardial infarction |
DOI: | 10.1016/j.ejheart.2007.05.014 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/601480/description#description |
Published version: | http://dx.doi.org/10.1016/j.ejheart.2007.05.014 |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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