Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/47167
Type: Journal article
Title: Synthesis of Substituted 4-amino-2-benzazepin-3-ones via N-acyliminium ion cyclizations
Author: Ballet, Steven
Urbanczyk-Lipkowska, Zofia
Tourwe, Dirk
Citation: Synlett, 2005; 18:2791-2795
Publisher: Thieme
Issue Date: 2005
ISSN: 0936-5214
School/Discipline: School of Chemistry and Physics : Chemistry
Abstract: Two versatile syntheses of 1⁻ and 1,2-disubstituted 2-benzazepinones are presented, using N-acyliminium ions as reactive intermediates. The methodology for 1-substitution is based on the synthesis of benzotriazole adducts, which are cyclized upon addition of AlCl₃. The simultaneous introduction of 1- and 2-substitions is realized by an N-acylation of an imine.
RMID: 0020082060
Appears in Collections:Chemistry and Physics publications

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