Adelaide Research & Scholarship
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https://hdl.handle.net/2440/47583
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| Type: | Journal article |
| Title: | Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines |
| Author: | Macreadie, I. Avery, T. Robinson, A. Macreadie, P. Barraclough, M. Taylor, D. Tiekink, E. |
| Citation: | Tetrahedron: the international journal for the rapid publication of full original research papers and critical reviews in organic chemistr, 2008; 64(7):1225-1232 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Issue Date: | 2008 |
| ISSN: | 0040-4020 |
| Abstract: | In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure–activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported. |
| Description: | Copyright © 2007 Elsevier Ltd All rights reserved. |
| DOI: | 10.1016/j.tet.2007.11.071 |
| Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/942/description#description |
| Appears in Collections: | Aurora harvest Chemistry publications |
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