Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/47583
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Type: Journal article
Title: Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines
Author: Macreadie, I.
Avery, T.
Robinson, A.
Macreadie, P.
Barraclough, M.
Taylor, D.
Tiekink, E.
Citation: Tetrahedron: the international journal for the rapid publication of full original research papers and critical reviews in organic chemistr, 2008; 64(7):1225-1232
Publisher: Pergamon-Elsevier Science Ltd
Issue Date: 2008
ISSN: 0040-4020
Abstract: In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure–activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were assessed primarily against the pathogenic yeast, Candida albicans, with haemolytic activity of selected examples also reported.
Description: Copyright © 2007 Elsevier Ltd All rights reserved.
DOI: 10.1016/j.tet.2007.11.071
Description (link): http://www.elsevier.com/wps/find/journaldescription.cws_home/942/description#description
Published version: http://dx.doi.org/10.1016/j.tet.2007.11.071
Appears in Collections:Aurora harvest
Chemistry publications

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