Adelaide Research & Scholarship
Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/4775
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| Type: | Journal article |
| Title: | Cytotoxicity of triorganophosphinegold(I) complexes of thiobenzoate |
| Author: | Vincent, Beverly R. Clarke, David John Smyth, Douglas Robert de Vos, Dick Tiekink, Edward Richard Tom |
| Citation: | Metal-Based Drugs, 2001; 8:79-84 |
| Publisher: | Hindawi |
| Issue Date: | 2001 |
| ISSN: | 0793-0291 |
| School/Discipline: | School of Chemistry and Physics School of Chemistry and Physics : Chemistry |
| Statement of Responsibility: | Beverly R. Vincent, David J. Clarke, Douglas R. Smyth, Dick de Vos, and Edward R. T. Tiekink |
| Abstract: | The preparation and characterization of two triorganophosphinegold(I) complexes containing the anion derived from thiobenzoic acid are described. The cytotoxicity of these complexes has been investigated along with that of triphenylphosphinegold(I) mercaptopurinate, a known anti-tumor compound, against a variety of human cell lines. The complexes showed moderate to high cytotoxicity (ID50 250 – 2500 ng/ml). |
| DOI: | 10.1155/MBD.2001.79 |
| Appears in Collections: | Chemistry publications |
Files in This Item:
| File | Size | Format | |
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| hdl_4775.pdf | 881.18 kB | Publisher's PDF | View/Open |
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