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Type: Journal article
Title: Cytotoxicity of triorganophosphinegold(I) complexes of thiobenzoate
Author: Vincent, Beverly R.
Clarke, David John
Smyth, Douglas Robert
de Vos, Dick
Tiekink, Edward Richard Tom
Citation: Metal-Based Drugs, 2001; 8:79-84
Publisher: Hindawi
Issue Date: 2001
ISSN: 0793-0291
School/Discipline: School of Chemistry and Physics
School of Chemistry and Physics : Chemistry
Statement of
Beverly R. Vincent, David J. Clarke, Douglas R. Smyth, Dick de Vos, and Edward R. T. Tiekink
Abstract: The preparation and characterization of two triorganophosphinegold(I) complexes containing the anion derived from thiobenzoic acid are described. The cytotoxicity of these complexes has been investigated along with that of triphenylphosphinegold(I) mercaptopurinate, a known anti-tumor compound, against a variety of human cell lines. The complexes showed moderate to high cytotoxicity (ID50 250 – 2500 ng/ml).
DOI: 10.1155/MBD.2001.79
Appears in Collections:Chemistry publications

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