Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/47841
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Type: Journal article
Title: A simple plan - cnidarians and the origins of developmental mechanisms
Author: Ball, E.
Hayward, D.
Saint, R.
Miller, D.
Citation: Nature Reviews Genetics, 2004; 5(8):567-577
Publisher: Nature Publishing Group
Issue Date: 2004
ISSN: 1471-0056
1471-0064
Organisation: Centre for the Molecular Genetics of Development
Abstract: Comparisons with cnidarians, long considered to be 'simple' animals, are providing crucial insights into the origins of conserved developmental mechanisms and the nature of the common metazoan ancestor. Traditionally, an extra germ layer and a second axis of body symmetry are the features that distinguish 'higher' Metazoa from lower animals such as cnidarians. Moreover, it was expected that 'lower' animals would have a simple gene set that corresponds to their simple morphology. Now, molecular genetic approaches are blurring the developmental divide between cnidarians and bilateral animals, and cnidarian sequencing projects are showing that the common metazoan ancestor was more genetically complex than was previously assumed.
Keywords: Muscles
Animals
Mice
Drosophila melanogaster
Cnidaria
Phylogeny
Gene Expression Regulation, Developmental
Models, Biological
DOI: 10.1038/nrg1402
Appears in Collections:Aurora harvest
Centre for the Molecular Genetics of Development publications

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