Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Enantioselective synthesis of α-fluorinated β²-amino acids|
|Other Titles:||Enantioselective synthesis of alpha-fluorinated beta(2)-amino acids|
|Citation:||Organic Letters, 2008; 10(5):885-887|
|Publisher:||Amer Chemical Soc|
|Michael K. Edmonds, Florian H. M. Graichen, James Gardiner, and Andrew D. Abell|
|Abstract:||A methodology for the enantioselective synthesis of α-fluorinated β²-amino acids has been developed from readily available carboxylic acids 3. Conversion to the Evan's oxazolidinone followed by enantioselective fluorination and alkylation gave 7 in high diastereomeric excess (>95%). Subsequent removal of the oxazolidinone and amination at the Bn-protected hydroxyl center gave optically active α-fluorinated β²-amino acids.|
|Description:||Copyright © 2008 American Chemical Society|
|Provenance:||Web Release Date: January 31, 2008|
|Appears in Collections:||Aurora harvest 6|
Chemistry and Physics publications
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.