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Type: Journal article
Title: Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34-/CD45-/glycophorin-A-bone marrow cells
Author: Zannettino, A.
Paton, S.
Kortesidis, A.
Khor, F.
Itescu, S.
Gronthos, S.
Citation: Haematologica, 2008; 92(12):1707-1708
Publisher: Ferrata Storti Foundation
Issue Date: 2008
ISSN: 0390-6078
Abstract: Magnetic and flow cytometry-based methods were used to characterize clonogenic stromal cells in human bone marrow. STRO-1(bright) stromal cells were found to lack expression of CD34, CD45 and glycophorin-A markers associated with hematopoietic progenitor cells. These studies support the view that these are two distinct stem cell compartments in adult bone marrow.
Keywords: Hematopoietic Stem Cells; Stromal Cells; Mesenchymal Stem Cells; Multipotent Stem Cells; Bone Marrow; Humans; Antigens, Differentiation; Antigens, CD34; Antigens, Surface; Flow Cytometry; Immunomagnetic Separation; Leukocyte Common Antigens; Glycophorins
RMID: 0020084164
DOI: 10.3324/haematol.11691
Appears in Collections:Medicine publications

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