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http://hdl.handle.net/2440/49021
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Type: | Journal article |
Title: | Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34-/CD45-/glycophorin-A-bone marrow cells |
Author: | Zannettino, A. Paton, S. Kortesidis, A. Khor, F. Itescu, S. Gronthos, S. |
Citation: | Haematologica, 2008; 92(12):1707-1708 |
Publisher: | Ferrata Storti Foundation |
Issue Date: | 2008 |
ISSN: | 0390-6078 1592-8721 |
Abstract: | Magnetic and flow cytometry-based methods were used to characterize clonogenic stromal cells in human bone marrow. STRO-1(bright) stromal cells were found to lack expression of CD34, CD45 and glycophorin-A markers associated with hematopoietic progenitor cells. These studies support the view that these are two distinct stem cell compartments in adult bone marrow. |
Keywords: | Hematopoietic Stem Cells; Stromal Cells; Mesenchymal Stem Cells; Multipotent Stem Cells; Bone Marrow; Humans; Antigens, Differentiation; Antigens, CD34; Antigens, Surface; Flow Cytometry; Immunomagnetic Separation; Leukocyte Common Antigens; Glycophorins |
RMID: | 0020084164 |
DOI: | 10.3324/haematol.11691 |
Appears in Collections: | Medicine publications |
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